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Borderline Personality Disorder Meetings- From the National Institute of Mental Health (NIMH)

Jim Breiling, Ph.D.
National Institute of Mental Health
6101 Executive Blvd., Room 6-179
Bethesda, MD 20892-9651
(Express or Courier Service: Rockville, MD 20852)
E-mail: jbreilin@mail.nih.gov 
Voice: 301-443-3527
Fax: 301-443-4611

Borderline Personality Disorder Meetings

June 15, 2004

The interest among researchers in attending the Borderline Personality Disorder treatment think tank has been unexpectedly strong -- and because so many of those who wanted to come are bright and able junior researchers who are our future, this interest has been most welcome, but we have now reached (indeed, slightly exceeded)
capacity. So, except for two special junior researchers who have been in communication with me about attending if they can arrange support, this meeting is closed to new registrations. We will be working with those attending the think tank to facilitate the dissemination of presentations and discussions there to the larger BPD research community.

Two Borderline Personality Research Foundation - NIMH meetings are in the works for early in 2005. One will address issues around the phenotype. The other will be a launch pad for a mentoring program for junior investigators who are viable applicants for NIMH grants for BPD research.. (With benefit of the ready assistance of a cadre of senior BPD treatment researchers, we will be launching this mentoring effort for search at the think tank.)


June 3, 2004

NIMH sponsors the annual New Clinical Drug Evaluation Unit (NCDEU) meeting.
Borderline PD has not yet made it as an explicit focus at NCDEU, but two treatment development sessions yesterday at this year's NCDEU meeting in Phoenix, Arizona, are close and relevant. These two sessions (see below) focused on impulsivity; one with a clinical treatment focus, the other drawing on basic research.

Emil Coccaro, who is well known to the borderline pd research community, was a presenter. James Blair of the NIMH intramural program, who presented at the second New Directions in Borderline Personality Research at the University of Minnesota, was also a presenter. William Potter of Eli Lilly was a participant in both panels.


Pharmacological treatment opportunities and issues will be one of the focuses at NIMH's international think tank July 8- 11 for the more effective treatment of borderline pd.
-- Jim Breiling


Thursday, June 3, 2004
Treatment Development Session 5
9:00 a.m. - 12:00 p.m. McArthur Salon 4

Impulsivity and Aggression as Clinical Treatment Targets

Chairs: Melissa DelBello, M.D., University of Cincinnati
Jeffrey A. Mattes, M.D., Psychopharmacology Research of Princeton

9:00 a.m. - 9:25 a.m. Impulsivity and Aggression across the Spectrum of Neuropsyhiatric Disorders
Emil Coccaro, M.D., University of Chicago

9:25 a.m. - 9:50 a.m. Neurobiology of Impulsivity in Children and Adolescents
James Blair, Ph.D., National Institute of Mental Health

9:50 a.m. - 10:15 a.m. Phenomenology and Overlap of Impulsivity and Aggression in Juvenile Bipolar Disorder, ADHD and Related Impulsivity Spectrum Disorders of Children and Adolescents
Janet Wozniak, M.D., Massachusetts General Hospital/Harvard Medical School

10:15 a.m. - 10:40 a.m. Measurement and Ratings of Impulsivity and Aggression in Children with ADHD, Bipolar and Related Disorders
Melissa DelBello, M.D.

10:40 a.m. - 11:05 a.m. Diagnostic and Methodologic Advances in Evaluating
Medication for Adult Intermittent Explosive Disorder
Jeffrey A. Mattes, M.D.

11:05 a.m. - 11:30 a.m. Industry Perspective on Treatment Development for
Impulsive Aggression
William Z. Potter, M.D., Ph.D., Eli Lilly and Company

11:30 a.m. - 11:45 a.m. Discussants
Eric Hollander, M.D., Mt. Sinai School of Medicine
Thomas P. Laughren, M.D., Food and Drug Administration

11:45 a.m. - 12:00 p.m. General Discussion

******************************************************************
Treatment Development Session 6
2:15 p.m. - 4:15 p.m. McArthur Salon 4

Models and Objective Measures Relevant to Impulsivity in Mental Disorders

Chair: Lois Winsky, Ph.D., National Institute of Mental Health

2:15 p.m. - 2:45 p.m. Preclinical Animal Models of Impulsivity: Strategies and Challenges
John L. Evenden, Ph.D., AstraZeneca Pharmaceuticals

2:45 p.m. - 3:15 p.m. Behavioral and Physiological Measures and Models of
Reward: Implications for Understanding Impulsivity
Brian Knutson, Ph.D., Stanford University

3:15 p.m. - 3:45 p.m. Comparative Assessment of Impulsive Behavior in Clinical and Animal Studies
Harriet de Wit, Ph.D., University of Chicago

3:45 p.m. - 4:15 p.m. Discussant
William Z. Potter, M.D., Ph.D., Eli Lilly and Company


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